CD Nelson Lecture
Desveaux, Darrell .
Type III Effectors and the Plant Immune Response.
The similarities between plant and animal innate immune systems and the common virulence mechanisms used by bacterial pathogens of plants and animals make the experimentally advantageous plant-pathogen system an ideal model to study bacterial pathogenesis of eukaryotic organisms. The plant pathogen Pseudomonas syringae causes disease on a large number of plant species using a type III secretion system that translocates effector proteins into plant cells. Our research focuses on understanding how pathogenic bacteria use type III effectors to manipulate host cell metabolism to favor infection and how plants have evolved to recognize these modifications in order to mount effective defense responses. Our efforts to identify the host targets of P. syringae type III effectors are shedding light on the molecular mechanisms of pathogen virulence and plant immunity. Importantly, extensive functional diversification is displayed by the molecular components at the plant-pathogen interface reflective of an evolutionary arms race that must be considered in the development of durable disease control strategies in agricultural settings.
Log in to add this item to your schedule
1 - Department of Cell and Systems Biology, Centre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, ON, M5S 3B2, Canada
Presentation Type: Special Presentation
Location: Salon 11/The Shaw Conference Centre
Date: Tuesday, July 28th, 2015
Time: 4:00 PM
Candidate for Awards:None