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Abstract Detail



Basic and applied approaches to improve disease resistance in plants

Despres, Charles [1].

The NPR1 Salicylic acid receptor: Trailblazing from basic science to commercialization.

Salicylic acid (SA) has been known for decades to be a mandatory plant metabolite in the deployment of immunity, specifically systemic acquired resistance (SAR). SAR is a broad-spectrum systemic immune response induced by local inoculation with avirulent pathogens. In 1997, a Syngenta legacy company identified NPR1 as the central protein positively regulating SAR. In 2000 we showed that NPR1 stimulates the binding of transcription factors of the TGA family to their DNA-sequence, linking NPR1 to gene regulation. In 2006 we determined that NPR1 is a transcriptional co-activator, establishing the molecular function of NPR1. In 2012, we demonstrated that NPR1 is a receptor for SA and the direct link between SA and gene activation. Armed with this latest discovery, my lab is now finally embarking on a path towards the application of basic science to agriculture.


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1 - Brock University, Biological Sciences, 500 Glenridge Ave., St. Catharines, ON, L2S 3A1, Canada

Keywords:
Arabidopsis
NPR1
salicylic acid
Receptor
Commercialization.

Presentation Type: Symposium Presentation
Session: SY05
Location: Salon 2/The Shaw Conference Centre
Date: Monday, July 27th, 2015
Time: 2:15 PM
Number: SY05003
Abstract ID:484
Candidate for Awards:None


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